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1. damage
Do you want to increase your damage?
1) Wearing equipment which compliments the current attack skill or spell you
are using. For example, the main stat of most spells is intelligence, so
you will want to be wearing equipment with high intelligence. Magicroll
will increase your spell damage output, and damroll will increase melee
damage and skill damage output.
2.) Your racial stats will affect your damage. You will want to inform
yourself about each race and their individual stats by using the 'race info
<name>' command.
3.) Use buffer skills and spells. Some buffers will increase your stats
temporarily and at the same time will be increasing your damage.
4.) The level of the skill/spell also plays a role into how much damage is
dealt.
5.) Train your class's main stat. Stats affect damage greatly. Help stats.
6.) Practice your skills and spells. Your skills and spells will do 50%
damage if you have only practiced them to 50% learned proficiency.
Do you want to decrease the amount of damage you take from enemies?
1.) Wear equipment with AC (armor class).
2.) Look for and wear items which have resistances on them.
3.) Use any skills and spells that give you resistances or immunities.